Pioneer:
- Amalia Benavides Aguirre is banned.
- Sorin, Imperious Bloodlord is banned.
Modern:
- Nadu, Winged Wisdom is banned.
- Grief is banned.
Legacy:
- Grief is banned.
Vintage:
- Urza’s Saga is restricted.
- Vexing Bauble is restricted.
Explorer:
- Amalia Benavides Aguirre is banned.
- Sorin, Imperious Bloodlord is banned.
It’s certainly up there.
The standard banning which hit the NEO meta, and the banning of the Mirrordin artifact lands are all up there too, but were I think more format specific.