At my last telehealth appointment, I asked my provider if I could switch to injections after reading some advice on here. Taking the strain off of my liver seems like it can only be a good thing!
I am scheduled for an instructional appointment tomorrow morning to learn how to administer them properly. Nervous, but looking forward to the change!
A note for everyone who is interested in injections but doesn’t like IM, you can also do subcutaneous injections. My understanding is that estradiol in common preparations is a depot injection where absorption is controlled less by physical factors and more from the lipophilicity of the medicine itself.
Anybody who’s interested can look for the article “Comparison of the Subcutaneous and Intramuscular Estradiol Regimens as Part of Gender-Affirming Hormone Therapy” published out of Dr. nippoldts group at Mayo recently.