Yeah, it really hasn’t been a hassle. At my workplace (software research, lots of which is actually x86-specific) many people have switched to Apple silicon Macs and nobody is looking back. The only issue I’ve noticed that is disruptive in any way is that Apple isn’t really supporting TAP based network adapters which causes trouble once in a while, mostly with certain vpn configurations. Standard development tools like IDEs, compilers, etc have worked since nearly day 1. Basically the only common targets that I wouldn’t develop for is Windows, but even then you can do it in a VM and it’s the fastest way to run windows on ARM still.